Chen-Yu Zhang Selected Research

dual inhibitor PTUPB

6/2020	A COX-2/sEH dual inhibitor PTUPB ameliorates cecal ligation and puncture-induced sepsis in mice via anti-inflammation and anti-oxidative stress.
1/2020	A COX-2/sEH dual inhibitor PTUPB alleviates lipopolysaccharide-induced acute lung injury in mice by inhibiting NLRP3 inflammasome activation.
1/2020	COX-2/sEH dual inhibitor PTUPB alleviates bleomycin-induced pulmonary fibrosis in mice via inhibiting senescence.

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Chen-Yu Zhang Research Topics

Disease

60	Neoplasms (Cancer) 11/2023 - 04/2007
14	Breast Neoplasms (Breast Cancer) 01/2021 - 03/2008
13	Carcinogenesis 01/2024 - 03/2010
13	Acute Lung Injury 01/2023 - 01/2019
13	Inflammation (Inflammations) 01/2023 - 05/2011
13	Colorectal Neoplasms (Colorectal Cancer) 01/2023 - 10/2008
12	Infections 01/2022 - 01/2009
12	Obesity 01/2021 - 04/2002
11	Lung Neoplasms (Lung Cancer) 10/2019 - 10/2008
8	Type 2 Diabetes Mellitus (MODY) 08/2017 - 11/2002
7	Neoplasm Metastasis (Metastasis) 01/2023 - 03/2008
6	Hyperglycemia 01/2021 - 12/2003
6	Fibrosis (Cirrhosis) 01/2020 - 12/2010
5	Non-alcoholic Fatty Liver Disease 12/2023 - 04/2002
5	Pulmonary Fibrosis (Fibrosing Alveolitis) 06/2023 - 01/2020
5	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2021 - 10/2008
5	Colitis 11/2019 - 12/2011
5	Hepatocellular Carcinoma (Hepatoma) 01/2018 - 12/2010
4	Renal Cell Carcinoma (Grawitz Tumor) 11/2023 - 01/2015
4	Insulin Resistance 03/2023 - 10/2014
3	Major Depressive Disorder (Major Depressive Disorders) 01/2024 - 10/2022
3	Lung Injury 12/2021 - 01/2020
3	Body Weight (Weight, Body) 01/2020 - 07/2006
3	Metabolic Diseases (Metabolic Disease) 01/2020 - 10/2015
3	Weight Loss (Weight Reduction) 01/2020 - 01/2015
3	Disease Progression 01/2019 - 03/2011
3	Pancreatic Neoplasms (Pancreatic Cancer) 10/2016 - 03/2012
3	Infertility (Sterility) 04/2016 - 12/2011
3	Atherosclerosis 08/2015 - 09/2008
2	Cognitive Dysfunction 01/2024 - 01/2015
2	Premature Aging 12/2023 - 01/2023
2	Osteosarcoma (Osteogenic Sarcoma) 01/2023 - 01/2016
2	Hypoxia (Hypoxemia) 10/2022 - 06/2010
2	Ulcerative Colitis 01/2022 - 12/2011
2	Brucellosis (Malta Fever) 01/2022 - 07/2019
2	Fever (Fevers) 01/2022 - 12/2019
2	COVID-19 11/2021 - 07/2021
2	Hyperlipidemias (Hyperlipidemia) 01/2021 - 02/2005
2	Liver Cirrhosis (Hepatic Cirrhosis) 01/2021 - 04/2012
2	Necrosis 01/2021 - 12/2019
2	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2021 - 01/2020
2	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 10/2020 - 01/2012
2	Fatty Liver 01/2020 - 04/2002
2	Hepatitis 01/2020 - 09/2014
2	Kidney Diseases (Kidney Disease) 01/2019 - 04/2013
2	Nephrotic Syndrome (Syndrome, Nephrotic) 01/2019 - 04/2013
2	Cardiovascular Diseases (Cardiovascular Disease) 10/2017 - 08/2015
2	Stomach Neoplasms (Stomach Cancer) 10/2017 - 03/2011
2	Diabetes Mellitus 05/2016 - 10/2015
2	Male Infertility (Male Sterility) 04/2016 - 12/2011
2	Chronic Hepatitis B 03/2016 - 12/2010
2	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 06/2015 - 05/2015

Drug/Important Bio-Agent (IBA)

76	MicroRNAs (MicroRNA)IBA 11/2023 - 10/2008
31	Proteins (Proteins, Gene)FDA Link 01/2024 - 08/2002
27	Biomarkers (Surrogate Marker)IBA 11/2023 - 10/2008
16	Messenger RNA (mRNA)IBA 12/2017 - 02/2005
9	Glucose (Dextrose)FDA LinkGeneric 01/2023 - 11/2002
8	InflammasomesIBA 01/2024 - 01/2020
7	LipopolysaccharidesIBA 11/2022 - 01/2019
6	LipidsIBA 12/2023 - 10/2016
6	CytokinesIBA 03/2023 - 08/2015
6	RNA (Ribonucleic Acid)IBA 01/2023 - 01/2015
6	Small Interfering RNA (siRNA)IBA 01/2023 - 03/2008
6	Arachidonic Acid (Vitamin F)IBA 07/2022 - 01/2020
4	Bleomycin (Blenoxane)FDA LinkGeneric 12/2022 - 01/2020
4	Insulin (Novolin)FDA Link 01/2021 - 12/2003
3	Nonesterified Fatty Acids (NEFA)IBA 12/2023 - 12/2004
3	Citric Acid (Citrate)FDA LinkGeneric 06/2023 - 12/2021
3	Long Noncoding RNAIBA 01/2023 - 06/2017
3	CollagenIBA 07/2022 - 10/2016
3	AcidsIBA 01/2022 - 05/2015
3	dual inhibitor PTUPBIBA 06/2020 - 01/2020
3	AntagomirsIBA 10/2016 - 06/2014
3	Uncoupling Protein 2IBA 11/2013 - 04/2002
3	Adenosine Triphosphate (ATP)IBA 06/2010 - 04/2002
2	Nucleic AcidsIBA 01/2024 - 12/2013
2	Galactose (Galactopyranose)FDA LinkGeneric 12/2023 - 01/2023
2	Urea (Carbamide)FDA LinkGeneric 01/2023 - 01/2012
2	Triggering Receptor Expressed on Myeloid Cells-1IBA 01/2023 - 12/2020
2	Therapeutic UsesIBA 10/2022 - 01/2022
2	Epoxide HydrolasesIBA 07/2022 - 12/2020
2	Sirtuin 1IBA 07/2022 - 01/2016
2	Triglycerides (Triacylglycerol)IBA 07/2022 - 01/2020
2	IntegrinsIBA 01/2022 - 09/2008
2	Piwi-Interacting RNAIBA 01/2022 - 04/2016
2	Galectin 1 (LGALS1)IBA 01/2020 - 10/2015
2	CateninsIBA 11/2019 - 03/2016
2	Dextran SulfateIBA 11/2019 - 01/2013
2	Indicators and Reagents (Reagents)IBA 07/2019 - 03/2016
2	Transcription Factors (Transcription Factor)IBA 10/2017 - 10/2015
2	LuciferasesIBA 01/2017 - 11/2016
2	mouse MIRN29 microRNAIBA 01/2016 - 04/2012
2	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 08/2015 - 09/2012
2	Dextrans (Dextran)FDA Link 06/2015 - 12/2011
2	Transforming Growth Factor beta Receptors (TGF beta Receptors)IBA 01/2015 - 01/2015

Therapy/Procedure

9	Therapeutics 03/2023 - 01/2016
2	Oral Administration 01/2021 - 10/2014
2	Ligation 06/2020 - 10/2013
2	Chinese Traditional Medicine (Traditional Chinese Medicine) 03/2019 - 01/2015
2	Drug Therapy (Chemotherapy) 12/2017 - 02/2012